The roles of 3′-exoribonucleases and the exosome in trypanosome mRNA degradation

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FIGURE 6.
FIGURE 6.

The effects of RNAi against PAN2 and RRP45 on genes encoding proteins of different functional classes. All unique ORFs were assigned into categories according to the function of the encoded protein. Those with mRNA stabilization or destabilization of at least twofold were selected, and the relative enrichment of each functional class was then calculated. Rows represent gene classes; columns represent the stabilized or destabilized mRNA. Each rectangle is colored to represent the log P-values for the enrichment of the corresponding functional category, according to Fisher’s test. The darker the pink color, the more significant the enrichment (see key).

This Article

  1. RNA 19: 937-947