FIGURE 3.
Effect of RNAi on the half-lives of trypanosome mRNAs. The half-life of the mRNA from each unique ORF in cells with RNAi is plotted against the half-life that was previously measured for wild-type cells, on a log scale. The dashed diagonal indicates perfect correlation. All half-lives >240 min were set to 240 min, and all ORFs with a steady-state RPM of <5 for any of the cell lines were excluded from the data set. RNAi was as follows: (A) PAN2; (B) RRP45; (C) CAF1; (D) CNOT10.
