The Runt domain of AML1 (RUNX1) binds a sequence-conserved RNA motif that mimics a DNA element

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FIGURE 5.
FIGURE 5.

2D NOESY spectrum of Apt1-S in D2O. The NOESY spectrum (mixing time = 400 msec) was recorded at 10°C, and cross peaks between aromatic H6 and H8 protons and ribose H1′ protons are shown. Sequential connectivities of the apical stem–loop (from C12 to G26) of Apt1-S are indicated by lines, and intraresidue NOEs are labeled by residues. The H1′ (G23) –H8 (G25) interresidue NOE is indicated.

This Article

  1. Published in Advance May 24, 2013, doi: 10.1261/rna.037879.112 RNA 19: 927-936

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