Visualizing RNA base-pairing probabilities with RNAbow diagrams

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FIGURE 3.
FIGURE 3.

Chemical mapping experiments indicate which bases are unpaired, and this information can also be visualized with Difference RNAbows. Here, for the 5′-UTR region of HIV-1, we compare the constrained (Schroeder et al. 2011) partition function where lowercase bases are forced to be unpaired (top, red) with the unconstrained partition function (bottom, blue).

This Article

  1. Published in Advance February 13, 2013, doi: 10.1261/rna.033365.112 RNA 19: 475-478

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