The central role of protein S12 in organizing the structure of the decoding site of the ribosome

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FIGURE 1.
FIGURE 1.

Location of SmD mutations affecting ribosomal protein S12. (A) Structure of the 30S ribosomal subunit from T. thermophilus (PDB entry 4DR1) (Demirci et al. 2013), indicating ribosomal protein S12 (purple) and 16S rRNA h44 (blue). (B) Close-up view of the decoding site, showing residues in ribosomal protein S12 (purple) mutated in SmD mutants identified in this and other studies. The upper portion of 16S rRNA h44 is colored blue and residues involved in monitoring codon recognition (G530, A1492, and A1493) and the site of the SmI mutation identified in this study are indicated.

This Article

  1. Published in Advance October 23, 2013, doi: 10.1261/rna.040030.113 RNA 19: 1791-1801

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