SplicerEX: A tool for the automated detection and classification of mRNA changes from conventional and splice-sensitive microarray expression data

U133 and HuEx arrays detect nonoverlapping changes in alternative mRNA processing. Comparison of genes detected, increased, decreased, and alternatively processed by array platform. Comparisons of increased, decreased, and alternatively processed gene lists were limited to genes detected on both the U133 and HuEx platforms. Genes were considered to be differentially expressed with p < 0.01 and fold change >2 between LCL (treatment) versus B-cell (reference) samples. Genes were considered to be alternatively processed if they had a positive splice score, SplicerEX p-val <0.01, and ANOVA p-val <0.01.