tRNAomics: tRNA gene copy number variation and codon use provide bioinformatic evidence of a new anticodon:codon wobble pair in a eukaryote

Species-specific improvement of the correlation of tRNA gene count and codon usage upon application of Sz. japonicus–adjusted wobbles. Four additional wobbles of U(NN) anticodons are added to the cerevisiae defined rules (Ala-TGC, Gly-TCC, Ser-TGA, Val-TAC) enabling decoding of the respective four-box through those tRNA genes. Although a significant improvement is seen for japonicus, little change is seen in correlation scores of most yeasts. Graphed data are numerically presented in Table 6.