tRNAomics: tRNA gene copy number variation and codon use provide bioinformatic evidence of a new anticodon:codon wobble pair in a eukaryote

Correlation of tRNA gene numbers and codon usage improves by parsing wobble pairs in the yeasts except Sz. japonicus. The number of tRNA genes represented as a fraction of the total was plotted against usage rate but parsing codons and isoacceptors for tRNA wobble, calculated for (A) the total proteome, (B) ribosomal proteins, and (C) transcription factors for the three yeast species shown, with Pearson correlation coefficients shown. Pearson correlation coefficients were calculated for each of the five yeasts in Table 4. Strong correlations are seen with the exception of Sz. japonicus.