tRNAomics: tRNA gene copy number variation and codon use provide bioinformatic evidence of a new anticodon:codon wobble pair in a eukaryote

Correlation of tRNA gene number and codon usage improves by partitioning highly expressed genes (ribosomal proteins) in the yeasts except Schizosaccharomyces japonicus. The number of tRNA genes represented as a fraction of the total for each amino acid was plotted against usage rate calculated for (A) the total proteome, (B) ribosomal proteins, and (C) transcription factors for the three yeast species shown, with Pearson correlation coefficients shown. Pearson correlation coefficients were calculated for each of the five yeasts in Table 4. Strong correlations are seen with the exception of Sz. japonicus.