Metal-ion rescue revisited: Biochemical detection of site-bound metal ions important for RNA folding

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FIGURE 5.
FIGURE 5.

Curves describing the variation of the Hill coefficient (nHill) with the divalent metal-ion folding midpoint according to models 1 (solid lines; see equation 5) and 2 (dashed lines; see equation 6) for folding of P4–P6 variants in Mg2+ (A) and in Mn2+ (B) in a background of 2 M NaCl. The data points are the experimentally estimated values of nHill and [M2+]1/2 for each individual RNA construct (Table 1).

This Article

  1. Published in Advance April 26, 2012, doi: 10.1261/rna.028738.111 RNA 18: 1123-1141

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