Metal-ion rescue revisited: Biochemical detection of site-bound metal ions important for RNA folding

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FIGURE 2.
FIGURE 2.

Model for equilibrium Mg2+- or Mn2+-induced folding of unmodified P4–P6 in a background of 2 M NaCl, which promotes the formation of a subset of long-range tertiary interactions. Two Mg2+ or Mn2+ ions bind within the A-rich bulge to form the final folded structure. (Adapted from Das et al. 2005b with permission from American Chemical Society © 2005.)

This Article

  1. Published in Advance April 26, 2012, doi: 10.1261/rna.028738.111 RNA 18: 1123-1141

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