Alternative ferritin mRNA translation via internal initiation

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FIGURE 6.
FIGURE 6.

The 5′ UTR of H-ferritin does not possess transcriptional activity. Firefly luciferase activity following transfection of HT1080 cells with (A) the pGL3Basic, pGL3Basic/Ftn(5′UTR), or pGL3Basic/NF-κB constructs, and (B) the pGL3Basic/NF-κB or pGL3Control constructs. The values from three independent experiments (mean ± SD) were normalized with Renilla luciferase activity from cotransfected pRL-TK.

This Article

  1. Published in Advance January 23, 2012, doi: 10.1261/rna.029322.111 RNA 18: 547-556

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