Rationalization and prediction of selective decoding of pseudouridine-modified nonsense and sense codons

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FIGURE 6.
FIGURE 6.

Predicting decoding of the ΨUU codon by tRNACys(GCA) and tRNATyr(GUA). (A) tRNA-mRNA base pairs between tRNACys(GCA) and ΨUU. (B) tRNA-mRNA base pairs between tRNATyr(GUA) and ΨUU. (C) tRNA-mRNA base pairs between tRNAPhe(GAA) and UUU taken from the crystal structure of 1IBM is also shown for comparison. The same color coding as from Figure 4 is used.

This Article

  1. Published in Advance January 26, 2012, doi: 10.1261/rna.031351.111 RNA 18: 355-367

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