Atomic-level insights into metabolite recognition and specificity of the SAM-II riboswitch

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FIGURE 6.
FIGURE 6.

Conformational space sampled by the expression platform of the SAM-II riboswitch in the free as well as SAM- and SAH-bound forms. (A) Projection of the configurations of the expression platform (nucleotides 46–51) on the first two Principal Components when the SAM-II riboswitch is free (black) and bound to either (S,S)-SAM (blue), (R,S)-SAM (green), or SAH (red). (B) Probability distribution of the configurations of the expression platform along the first Principal Component. The color code is the same as in A.

This Article

  1. Published in Advance December 22, 2011, doi: 10.1261/rna.028779.111 RNA 18: 300-307

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