The essential polysome-associated RNA-binding protein RBP42 targets mRNAs involved in Trypanosoma brucei energy metabolism

Gene Ontology (GO) assignments for RBP42-bound mRNAs. Highly significant (P < 0.01) associations of RBP42 targets with GO terms are shown. GO terms are derived from a GO Slim set designed to incorporate trypanosome-specific processes and cellular compartments (Alsford et al. 2011). GO terms that describe broad categories are indicated by light blue bars; GO terms that describe specific categories are indicated by dark blue bars. Statistical analysis of GO term associations was carried out using 137 annotated genes. Since annotated genes lack a comprehensive set of appropriate GO terms, each significant association was verified.