Analysis of the accessibility of CLIP bound sites reveals that nucleation of the miRNA:mRNA pairing occurs preferentially at the 3′-end of the seed match

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FIGURE 5.
FIGURE 5.

Average accessibility of the nucleation region as a function of its location within the seed match. (A–F) Average accessibility is shown for both bound and unbound sites and for all possible n-mers. Statistical significance was evaluated with the one-sided Wilcoxon rank sum test.

This Article

  1. Published in Advance August 22, 2012, doi: 10.1261/rna.033282.112 RNA 18: 1760-1770

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