DAZAP1, an RNA-binding protein required for development and spermatogenesis, can regulate mRNA translation

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 6.
FIGURE 6.

DAZAP1-mediated stimulation is enhanced by the presence of multiple binding sites within the 3′ UTR. Oocytes expressing MS2-U1A and MS2-xDAZAP1 were co-injected with β-galactosidase control and luciferase reporter mRNAs containing one (luc-MS21), three (luc-MS23), or nine (luc-MS29) MS2-binding sites within the 3′ UTR. luc-MS23 is referred to as luc-MS2 elsewhere. Data are plotted as in Figure 1A.

This Article

  1. Published in Advance May 16, 2011, doi: 10.1261/rna.2717711 RNA 17: 1282-1295

Current Issue

  1. July 2026, 32 (7)
  1. Current Issue
  1. Alert me to new issues of RNA