DAZAP1, an RNA-binding protein required for development and spermatogenesis, can regulate mRNA translation

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 5.
FIGURE 5.

ERK phosphorylation does not regulate the translational stimulatory activity of DAZAP1. Tethered-function assays in stage VI (A) and mature oocytes (A,B) expressing (A) MS2-xDAZAP1 or (B) wild-type MS2-hDAZAP1 or MS2-hDAZAP1 containing phosphomutant (AA) or phosphomimetic residues (DD). Reporter and internal control mRNAs were used, and the data are plotted as in Figure 1A.

This Article

  1. Published in Advance May 16, 2011, doi: 10.1261/rna.2717711 RNA 17: 1282-1295

Current Issue

  1. July 2026, 32 (7)
  1. Current Issue
  1. Alert me to new issues of RNA