The RNR motif of B. subtilis RNase P protein interacts with both PRNA and pre-tRNA to stabilize an active conformer

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FIGURE 2.
FIGURE 2.

(A) Binding of P protein to PRNA. Wild-type data are displayed in solid triangles (solid line), R60A in open circles (dashed line), and R62A in solid squares (filled line). (B) Relative affinities of PRNA for RNR P protein mutants (white bars; KD,holo,mutant/KD,holo,wild-type) and RNase P holoenzymes reconstituted with RNR motif protein mutants for pre-tRNAAsp (gray bars; KD,pre-tRNA,mutant/KD,pre-tRNA,wild-type).

This Article

  1. Published in Advance May 27, 2011, doi: 10.1261/rna.2742511 RNA 17: 1225-1235

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