Identification of potential conserved RNA secondary structure throughout influenza A coding regions

Segment 8 sequence from nucleotides 100–125 compared to amino acid coding for region with mutations reported by Ilyinskii et al. (2009). The top row has the alignment positions. Below are given the consensus amino acid sequence and primary nucleotide sequence. Position 102 is a C to represent the consensus sequence for this region, but a U is used at this position in Figure 5 to more accurately represent the canonical pairing in the structural model. Natural occurrences of the NS1mut3841 mutations made by Ilyinskii et al. (2009) are underlined, while the mutations never observed naturally are boxed.