Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae

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FIGURE 6.
FIGURE 6.

Knockdown of human TRM140 decreases m3C formation. LC/MS nucleoside analysis of RNA from cells treated with shRNAs targeting GFP (left) and hTRM140 (right). (Top, bottom) Mass chromatograms detecting MH+ (m/z 258) and BH2+ (m/z 126) of m3C and m5C, respectively.

This Article

  1. Published in Advance April 25, 2011, doi: 10.1261/rna.2653411 RNA 17: 1111-1119

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