FIGURE 1.
Double-stranded RNA-induced conductance increases in Drosophila S2 cells expressing SID-1. (A) Changes in whole-cell conductance of a SID-1(WT) (circles) or a SID-1(S536I) (squares) expressing cell in response to dsRNA addition to (white-filled circles) and subsequent replacement of the bath solution (gray-filled circles). (B) The addition of dsDNA (black-filled circles) and then dsRNA (white-filled circles) to the bath solution of a patched, SID-1(WT) expressing S2 cell at the indicated sweeps.
