Potent and systematic RNAi mediated silencing with single oligonucleotide compounds

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FIGURE 3.
FIGURE 3.

Identification of highly potent soloRNA compounds. A panel of soloRNAs corresponding (identical seed region) to previously identified functional 25-bp RNAi duplexes against the SOD1 gene were transfected at 1 nM into HEK293 cells. SOD1 expression (normalized to PPIB) was evaluated at 48 h using a bDNA assay. Error bars represent the standard deviation of biological triplicates.

This Article

  1. Published in Advance April 14, 2011, doi: 10.1261/rna.2399411 RNA 17: 1032-1037

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