Proofreading and spellchecking: A two-tier strategy for pre-mRNA splicing quality control

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FIGURE 3.
FIGURE 3.

External spellchecking mechanisms for splicing products. RNA degradative pathways for mRNAs that have escaped splicing or contain splicing mistakes. For simplicity purposes, the ribosome stalled at the PTC is not shown for the spliced mRNA that has been incorrectly spliced.

This Article

  1. Published in Advance January 4, 2011, doi: 10.1261/rna.2454711 RNA 17: 383-389

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