DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures

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FIGURE 8.
FIGURE 8.

Models of how DGCR8 recognizes pri-miRNAs. (A) The cooperative recognition of pri-miRNAs by DGCR8. (B) Formation of proper higher-order structure of DGCR8–pri-miRNA complexes. For details, see the main text.

This Article

  1. Published in Advance June 17, 2010, doi: 10.1261/rna.2111310 RNA 16: 1570-1583

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