Autoregulation of Fox protein expression to produce dominant negative splicing factors

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FIGURE 7.
FIGURE 7.

Fox-2ΔE6 does not alter Fox-dependent splicing repression. HEK293 cells were transfected with the minigene DUP-E9*CACNA1Cwt, containing a middle exon inhibited by Fox. FLAG-Fox-2 and FLAG-Fox-2ΔE6 were cotransfected into these cells as in Figures 5 and 6. The splicing of the middle exon and the expression of the Fox proteins were determined as above.

This Article

  1. Published in Advance December 30, 2009, doi: 10.1261/rna.1838210 RNA 16: 405-416

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