The nuclear experience of CPEB: Implications for RNA processing and translational control

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FIGURE 4.
FIGURE 4.

CPEB contains two redundant NESs in the N-terminal half of the protein. (A) When both of the NESs were mutated, CPEB accumulated in the nucleus independently of LMB treatment. (B) An alignment shows these two NESs are conserved among species. The critical leucine/isoleucine residues are also conserved in Drosophila orb1, but not other CPEB family proteins of any species (not shown).

This Article

  1. Published in Advance December 29, 2009, doi: 10.1261/rna.1779810 RNA 16: 338-348

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