Metal binding and substrate positioning by evolutionarily invariant U6 sequences in catalytically active protein-free snRNAs

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FIGURE 8.
FIGURE 8.

Terbium(III) cleavage reactions on folded U6/U2 complexes. Lane marked control does not contain Terbium (Tb+++). The concentration of the added terbium(III) in micromolars is indicated above each lane. The location of unreacted U6/U2 and the position of several residues in U6 is shown to the right.

This Article

  1. Published in Advance September 8, 2010, doi: 10.1261/rna.2170910 RNA 16: 2226-2238

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