Morpholino oligonucleotides do not participate perfectly in standard Watson-Crick complexes with RNA

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 2.
FIGURE 2.

Order of reactions: Amount of cleavage as a function of concentration of the added EGS. (A) CATEGS; (B) CATPPMO; (C) CATPMO. The concentration of added of the particular EGS oligonucleotide is given as a high ratio to the mRNA substrate as indicated in the abscissa of the figure.

This Article

  1. Published in Advance September 3, 2010, doi: 10.1261/rna.2256610 RNA 16: 2218-2225

Current Issue

  1. August 2026, 32 (8)
  1. Current Issue
  1. Alert me to new issues of RNA