Specific and global regulation of mRNA stability during osmotic stress in Saccharomyces cerevisiae

General mRNA stabilization during severe osmotic stress (1 M KCl). (A) Half-lives of RPS31, URA1, and DSE2 mRNAs in strain PAY500 (rpb1-1^ts ) and of RTN2 mRNA in strain PAY498 (rpb1-1^ts tetO₂ -RTN2) were measured as described in Figure 2. The half-life value of a representative experiment is shown. (B) Half-life change (%) after severe osmotic stress in a wt strain. Means were calculated from at least three independent experiments. Error bars represent the standard deviation.