Equal transcription rates of productively and nonproductively rearranged immunoglobulin μ heavy chain alleles in a pro-B cell line

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FIGURE 3.
FIGURE 3.

Effect of histone deacetylase inhibitors on relative mRNA abundances of the productively and the nonproductively rearranged Ig-μ alleles. (A) TSA at two different concentrations (5 and 25 ng/mL) was added to the cells for 24 h before RNA isolation. (B) Cells were incubated with 1 or 3 mM SB for 24 h before RNA isolation. Relative mRNA abundances were determined by RT-qPCR as in Figure 2D.

This Article

  1. Published in Advance April 10, 2009, doi: 10.1261/rna.1516409 RNA 15: 1021-1028

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