FIGURE 1.
Primary structure similarity between human and archaeal Clp1. The amino acid sequence of P. horikoshii Clp1 (Pho) is aligned to the homologous polypeptide encoded by H. sapiens (Hsa). Gaps in the alignment are indicated by dashes. Positions of amino acid side chain identity or similarity are indicated by dots. The amino acids subjected to alanine substitution (Lys49 and Asp73) are highlighted and indicated by |.
