Structure of the cytosine–cytosine mismatch in the thymidylate synthase mRNA binding site and analysis of its interaction with the aminoglycoside paromomycin

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FIGURE 9.
FIGURE 9.

Widening of the major groove in the TSMC RNA containing a CC mismatch. (A) Surface representation of the structure of TSMC and (B) model of an RNA, containing a GC Watson–Crick base pair in place of the CC mismatch, and a fully A-form stem. The CC mismatch in A and the corresponding GC base pair in B are colored blue.

This Article

  1. Published in Advance March 27, 2009, doi: 10.1261/rna.1514909 RNA 15: 911-922

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