Tailoring RNA modular units on a common scaffold: A modular ribozyme with a catalytic unit for β-nicotinamide mononucleotide-activated RNA ligation

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FIGURE 2.
FIGURE 2.

Sequence comparison of the YFL-1 and its variants isolated from the first and second selections. (A) Sequences of 38 clones from the first selection. (Asterisks) The YFL-1 sequences were found in 28 independent clones. (B) Sequences of 26 clones from the second selection. (Asterisks) The YFL-1 sequences were found in seven independent clones. (Dashes) The bases that are the same as in YFL-1. Slashes in position R40 of clones d-16, 22, and 24 indicate single-nucleotide deletions.

This Article

  1. Published in Advance March 23, 2009, doi: 10.1261/rna.1461309 RNA 15: 877-888

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