Polyadenylation releases mRNA from RNA polymerase II in a process that is licensed by splicing

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 7.
FIGURE 7.

Splicing remodels the EDC. Pull-down Method 2 was used. The spliced/unspliced pull-down efficiencies were calculated as an average of the two ways in which the splicing of each intron can occur, as illustrated in the table. For lanes 1 and 2 the average and range for two independent experiments is given. Lanes 5 and 6 are from a different experiment.

This Article

  1. RNA 15: 823-836