Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells

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FIGURE 2.
FIGURE 2.

Lin28 associates with a specific subset of mRNAs. (A) Flag-Lin28 was transfected into mouse ES cells. Immunoprecipitation (IP) was carried out 24 h later and RNP-associated RNAs analyzed by RT-qPCR. mRNA levels present in the anti-Flag relative to control IgG complexes are shown. Each bar represents mean ± SD (n = 3). (B) Steady-state mRNA levels plotted relative to those of β-actin mRNA. Each bar represents mean ± SD (n = 3).

This Article

  1. Published in Advance January 15, 2009, doi: 10.1261/rna.1368009 RNA 15: 357-361

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