FIGURE 3.
Teratoma-like primordial tissues derived from the mirPS EB implants in the uterus or peritoneal cavity of female pseudopregnant immunocompromised SCID-beige mice (n/total = 6/6). These differentiated tissues included all three embryonic germ layers—ectoderm, mesoderm, and endoderm, as determined by their distinct cell morphologies after hematoxylin and eosin (H & E) staining. Photographs were taken with the Nikon TE2000 microscopic system at 200× magnification.
