Long-distance placement of substrate RNA by H/ACA proteins

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 6.
FIGURE 6.

Distinct substrate RNA conformations in partially and fully docked complexes are revealed by fluorescence studies. A cartoon representation of substrate conformations accounting for the observed fluorescence intensities. “U” denotes the target uridine and the fused rings represent 2-AP. Yellow cylinders represent the four helices formed by the guide–substrate RNA complex.

This Article

  1. RNA 14: 2086-2094