The sarcin–ricin loop of 23S rRNA is essential for assembly of the functional core of the 50S ribosomal subunit

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FIGURE 6.
FIGURE 6.

Deletion of the SRL causes structural changes in 23S rRNA. Primer-extension analysis of 23S rRNA extracted from WT or ΔSRL 50S subunits probed with D, dimethylsufate, or K, kethoxal. A and G are sequencing lanes; (−) unmodified subunits. Arrows indicate bases with altered reactivity in ΔSRL 50S subunits as compared to WT.

This Article

  1. Published in Advance August 28, 2008, doi: 10.1261/rna.1202108 RNA 14: 1999-2012

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