Breaking pseudo-twofold symmetry in the poliovirus 3′-UTR Y-stem by restoring Watson–Crick base pairs

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FIGURE 1.
FIGURE 1.

(A) Schematic representation of the secondary structure of the 3′-UTR of poliovirus type 1. (B) RNA hairpin Ycu and (C) hairpin Yuu used for the NMR studies. Variation of the central two base pairs in the Y domain is shown on the left of the Y domain in A for the polio and polio-like coxsackie viruses, for the nonpolio-like coxsackie and ECHO viruses on the right.

This Article

  1. RNA 13: 781-792