Global analysis of exon creation versus loss and the role of alternative splicing in 17 vertebrate genomes

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FIGURE 1.
FIGURE 1.

Outgroup method for distinguishing between creation and loss. (A) Exon is present in the source and outgroup organism, which implies that the ancestral state is also present. This means that the exon was lost from the target organism after the split with source. (B) Exon is not present in either the target or outgroup organism; therefore, it must have been created after the split of source and target.

This Article

  1. Published in Advance March 16, 2007, doi: 10.1261/rna.325107 RNA 13: 661-670

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