FIGURE 1.
Structure of the EST3 gene and frameshift region. The diagram at the bottom shows the arrangement of the two open reading frames and the frameshift site (FS) within the overlap region. Above is the DNA sequence of the heptameric frameshift site (white letters on black) and the 30 nt both upstream and downstream. Below the DNA sequence is the encoded protein product in the zero (above) and +1 (below) reading frames with the amino acids encoded into the frameshift product in black and the arrow indicating decoding by frameshifting. The extent of three oligonucleotides referred to in Figure 2 (EST3 67 mer, 5′ 37 mer, and 3′ 37 mer are indicated above the DNA sequence.
