A computational proposal for designing structured RNA pools for in vitro selection of RNAs

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FIGURE 9.
FIGURE 9.

Comparison of designed GTP (upper) and random (lower) pools using contour plots of Hamming distance versus tree edit distance. The GTP pool is generated by 62.5% MM13 starting with the 52 motif (Fig. 3D) and 37.5% MM10 starting with the 42 motif (Fig. 3F). The random pool is generated using the starting sequence in Figure 3D.

This Article

  1. Published in Advance February 23, 2007, doi: 10.1261/rna.374907 RNA 13: 478-492

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