A computational proposal for designing structured RNA pools for in vitro selection of RNAs

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FIGURE 3.
FIGURE 3.

Starting sequences and their secondary structures for pool synthesis using mixing matrices. Displayed are the secondary structures and corresponding tree graphs for four existing and two modified existing RNAs. Laplacian eigenvalue (λ2) of the tree graph indicates the structural complexity.

This Article

  1. Published in Advance February 23, 2007, doi: 10.1261/rna.374907 RNA 13: 478-492

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