Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 3.
FIGURE 3.

(A) Distribution of changes in mRNA levels in six mutant populations compared with the wild type for 17,774 C. elegans genes, as assayed by microarray hybridization (see Materials and Methods). Only transcripts that increased or decreased at least twofold are shown. (B) Venn diagram of genes elevated twofold or more in mutants of rrf-3(pk1426) (129 genes), rrf-1(pk1417) (221 genes), rde-3(ne298) (257 genes), and eri-1(mg366) (274 genes).

This Article

  1. RNA 12: 589-597