FIGURE 3.
The RNA Ontology will facilitate the integration of heterogeneous RNA data including experimental 3D structures (upper left) and nucleotide sequences (lower left). The RNA Ontology will represent information about RNA in ways that are comprehensible by humans (upper right) and machines (lower right). (Here the sarcin motif is annotated for strand continuity and base-pairing relations as for input scripts for the programs MC-Sym—for 3D modeling—and MC-Search—for 3D motif searching [Gautheret et al. 1993; Hoffmann et al. 2003].) Machine annotation will facilitate automation of processes such as sequence alignment, by exploiting all relevant 3D structure data.
