The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells

TABLE 1.

siRNAs and respective siRNA target sequence used in the HIV-1 U3 targeting

siRNA (Position) Sequence (Target) % GC
247 (249–267 in LTR of HIV subtype B) GTGTTAGAGTGGAGGTTTG 47.4
362 (354–372 in LTR of HIV subtype B) CTTTCCGCTGGGGACTTTC 57.9
GFP (108–126 in GFP mRNA) CGATGCCACCTACGGCAAG 63.2
R5 Control (787–805 in CCR5 mRNA) TTCTTTGGCCTGAATAATT 31.6

This Article

  1. Published in Advance December 22, 2005, doi: 10.1261/rna.2235106 RNA 12: 256-262

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