The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells

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FIGURE 4.
FIGURE 4.

Biotin-labeled antisense siRNA EF52 (AS+Biotin) coprecipitates with trimethylated H3K27, Flag-tagged DNMT3A, and the targeted EF1A promoter, while the sense EF52 (S+Biotin) does not. Results are representative of two independent experiments.

This Article

  1. Published in Advance December 22, 2005, doi: 10.1261/rna.2235106 RNA 12: 256-262

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