Prp8 protein: At the heart of the spliceosome

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FIGURE 1.
FIGURE 1.

Schematic diagram showing the assembly and recycling of spliceosome components with respect to Prp8. The conserved 5′ and 3′ splice sites represent the U2 cis-spliceosomal GU and AG residues, respectively. Prp8 has been found in two different U5 complexes: the U5 snRNP (small, yellow) and the larger U5/Prp19 snRNP (large, blue). (Adapted with permission from Makarov et al. © 2002 AAAS [www.sciencemag.org].)

This Article

  1. RNA 11: 533-557

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