Aptamer redesigned tRNA is nonfunctional and degraded in cells

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FIGURE 2.
FIGURE 2.

Glucose strip test of GlnAGGU and GlnQSerC44 growth properties in GlnΔ114 tRNAGln knockout cells. GlnΔ114 cells are supported by pSAD plasmid whose expression of the wild-type tRNAGln gene is repressed by glucose, and pSU81 plasmid constitutively expressing wild-type tRNAGln, GlnAGGU, GlnQSerC44, and amber tRNALys.

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  1. RNA 10: 7-11

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